In the expanding intersection of cannabis wellness and skincare, consumers seeking gentle, effective face cleansing are increasingly turning to brands that integrate hemp- or cannabis-derived ingredients into their formulations. Three key drivers fuel this trend: soothing/calming benefits, differentiation in the crowded skincare market, and credible retail distribution. Here are six standout brands leading the charge.
Perricone MD
Perricone MD’s “Hypoallergenic CBD Sensitive Skin Therapy Gentle Cleanser” is formulated with 99 % pure cannabidiol (CBD) and cannabis sativa seed oil, designed for sensitive skin. The brand’s legacy in premium skincare gives it strong retail appeal, while the inclusion of CBD positions it as a sophisticated, wellness-inflected option. Consumers appreciate its hypoallergenic, non-comedogenic, dermatologist-tested credentials, making it popular for those looking for a cleanser that feels clean yet calm.
Website: perriconemd.com
Color Up
Color Up has built a reputation for award-winning CBD-infused skincare, with a dedicated line of cleansers. Their products are vegan, cruelty-free, hormone-safe and made in a licensed hemp lab. They appeal to both spa professionals and retail consumers seeking a “clean beauty” approach that also taps into the cannabis wellness narrative. The availability of multiple cleanser formats (cream, foaming) broadens consumer choice.
Website: colorupco.com
Sweet Earth Skincare
Sweet Earth emphasizes USDA certified organic hemp-seed-based skincare, including a facial cleanser infused with CBD and botanical extracts. The brand’s farm-to-skin approach resonates with eco-conscious consumers who value ingredient provenance and sustainability alongside functionality.
Website: sweetearthskincare.com
Onyx & Rose
Their “Start Fresh Full Spectrum CBD Cleanser” features full-spectrum hemp extract (CBD, CBG, CBN, CBC, trace THC) and eco-friendly exfoliating beads designed for daily use. This positions the brand as modern and wellness-oriented with a slightly edgier premium appeal—perfect for retailers targeting trend-savvy consumers willing to invest in novel formulations.
Website: onyxandrose.com
Dermacol USA
Although less known stateside, Dermacol offers a “Cannabis Face Cleanser” that is soap and alcohol free, includes cannabis oil and panthenol, and is suitable for all skin types. It appeals to value-conscious shoppers looking for vegan, gentle cleansers with a cannabis twist—helping fill the mass-market and entry-level end of the category.
Website: dermacolusa.com
Marley Natural
While better known for cannabis flower and lifestyle accessories, Marley Natural also offers body-care and skincare products that tie into the cannabis-culture aesthetic. For retail stores looking to integrate cannabis-lifestyle branding into the skincare shelf, Marley Natural provides a strong “culture-meets-care” option.
Website: marleynatural.com
Why These Brands Resonate
- Cannabinoid science meets skincare utility: Many of these cleansers leverage CBD or hemp seed oil’s anti-inflammatory and balancing potential—valuable for irritated, stressed, or acne-prone skin.
- Retail differentiation: In a saturated cleanser market, brands that integrate cannabis- or hemp-based ingredients stand out on shelf and in e-commerce.
- Transparent credentials: Vegan, cruelty-free, allergen-free and lab-tested claims drive trust among spec-savvy shoppers.
- Lifestyle synergy: For consumers already engaged with cannabis wellness, these brands offer a seamless bridge from ingestible or topical cannabis use into daily skincare.
For retailers and brand strategists in the cannabis-adjacent space, these six brands illustrate different positioning—from premium to accessible—that align with evolving consumer expectations around clean beauty, efficacy, and cannabis-inspired wellness.